Modifications of Cellular RNA-polymerase II after Infection with Frog Virus 3
- 1 June 1975
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 27 (3) , 391-394
- https://doi.org/10.1099/0022-1317-27-3-391
Abstract
Summary RNA-polymerase II extracted from FV3-infected and uninfected BHK cells were compared by measuring their abilities to bind [3H]-amanitin and ribonucleoside triphosphates. Binding sites for [3H]-amanitin and the dissociation constant of the complex between [3H]-amanitin and RNA-polymerase II were significantly modified following FV3 infection. The apparent Km's for ribonucleoside triphosphates remained unchanged.Keywords
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