In Vitro Activity of Linezolid against Slowly Growing Nontuberculous Mycobacteria
Open Access
- 1 May 2003
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (5) , 1736-1738
- https://doi.org/10.1128/aac.47.5.1736-1738.2003
Abstract
MICs of linezolid in broth microdilutions were tested against 341 slowly growing nontuberculous mycobacteria (NTM) belonging to 15 species. The proposed linezolid susceptibility MICs for all Mycobacterium marinum , Mycobacterium szulgai , Mycobacterium kansasii , Mycobacterium malmoense , and Mycobacterium xenopi isolates and for 90% of Mycobacterium gordonae and Mycobacterium triplex isolates were ≤8 μg/ml. Linezolid has excellent therapeutic potential against most species of NTM.Keywords
This publication has 6 references indexed in Scilit:
- Clinical Experience with Linezolid for the Treatment ofNocardiaInfectionClinical Infectious Diseases, 2003
- In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis That Are Susceptible or Resistant to First-Line Antituberculous DrugsAntimicrobial Agents and Chemotherapy, 2003
- Successful Treatment of DisseminatedMycobacterium chelonaeInfection with LinezolidClinical Infectious Diseases, 2001
- In Vitro Activities of Linezolid against Multiple Nocardia SpeciesAntimicrobial Agents and Chemotherapy, 2001
- Activities of Linezolid against Rapidly Growing MycobacteriaAntimicrobial Agents and Chemotherapy, 2001
- Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial TaxonomyInternational Journal of Systematic and Evolutionary Microbiology, 1999