HL-A Frequencies in Crohn's Disease and Ulcerative Colitis

Abstract
Sixty-two patients with Crohn''s disease and 51 with ulcerative colitis were HL-A typed. Phenotype frequencies were calculated and compared with those of a control group of 335 individuals. A higher frequency of HL-A17 was found among the Crohn''s disease patients, but this was not significant. HL-A17 was included in 2 studies on Crohn''s disease; the combined relative risk is 3.24, which significantly deviates from 1 unity. No statistically significant differences in the HL-A antigen distribution were found among the patients with ulcerative colitis.