Prophylaxis of Bacteriuria During Intermittent Catheterization of the Acute Neurogenic Bladder

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Abstract
A randomized prospective study of bacteriura control during early intermittent bladder catheterization was performed on a spinal cord injury service. The 64 male subjects underwent 16,620 catheterizations and had 83 significant episodes of infection. The infection rates among various groups were compared: control patients, patients treated with intravesical neomycin/polymyxin-B; patients given low dose daily macrocrystals of nitrofurantoin; and patients given intravesical treatment and oral nitrofurantoin. There was significant reduction in infection rates when oral and intravesical antibiotics were used.