Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene
- 1 January 1997
- journal article
- research article
- Published by Wolters Kluwer Health in Psychiatric Genetics
- Vol. 7 (2) , 83-86
- https://doi.org/10.1097/00041444-199722000-00005
Abstract
An association study of 97 patients with DSM-III-R schizophrenia and 97 matched controls was performed using a polymorphic microsatellite repeat at the dopamine D5 receptor gene. We observed a significant difference between the allele frequencies of patients and controls (X2 = 23.4, df = 12, p = 0.019). This reflects an excess of allele 4 (140 bp) in the patients when compared with the control sample (X2 = 7.087, pKeywords
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