The Therapeutic Value of Mercurochrome, Hexamethylenamin, and Hexylresorcinol in Cases of Experimental Urinary Infection in Rabbits

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Abstract
Therapeutic results were studied in infections in rabbits produced by intravenous and intracystic injection of the colon bacillus and Staphylococcus albus. In the intracystic injections the bacteria were suspended in 5% starch solution. In each type of infection there was a control group, a group treated with hexylresorcinol, 1 with hexamethylenamin, and 1 with mercurochrome. The experiments in intracystic injection of S. albus were a complete failure because the organism disappeared from the urine rapidly and showed no tendency to localize and produce inflammation in the bladder. In the dosages used, hexamethylenamin was superior to mercurochrome and hexylresorcinol as a urinary antiseptic in cases of infection produced by S. albus and the colon bacillus. S. albus was much more susceptible to the action of hexamethylenamin than was the colon bacillus.

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