Decreased chemotactic and random migration of leukocytes during Intralipid infusion
Open Access
- 1 December 1979
- journal article
- clinical trial
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 32 (12) , 2416-2422
- https://doi.org/10.1093/ajcn/32.12.2416
Abstract
The soybean oil emulsion Intralipid was given intravenously to 12 healthy subjects for 2 nr. During the infusion an impairment of the chemotactic and random migration of leukocytes was noted. It was correlated to the dose given and to the degree of hypertriglyceridemia induced. Migration was fully restituted 22 hr after the infusion. Also when added in vitro Intralipid caused an impairment of leukocyte motility that followed a dose response pattern.Keywords
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