FAILURE OF PROPHYLACTIC ANTIMICROBIAL DRUG TO PREVENT SEPSIS AFTER FIBEROPTIC BRONCHOSCOPY

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Abstract
A 53-yr-old patient with lymphoblastic lymphoma developed progressive interstitial pulmonary infiltrates. The patient apparently had Pseudomonas bronchitis and was given parenteral gentamicin. Transbronchial lung biopsy performed through a fiberoptic bronchoscope was complicated by development of Pseudomonas septicemia. The organism isolated on blood culture, like the one isolated on sputum culture, was fully susceptible to gentamicin in vitro. A prophylactic antimicrobial drug did not prevent bacteremic Pseudomonas infection in the immunosuppressed patient with pre-existent Pseudomonas bronchitis.

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