Synthesis of (2S,5S)-2,5-Bis(phenylmethyl)piperazine by the Reduction with Sodium Borohydride Using Titanium Tetrachloride
- 1 January 1986
- journal article
- research article
- Published by The Japan Institute of Heterocyclic Chemistry in HETEROCYCLES
- Vol. 24 (5) , 1287-1289
- https://doi.org/10.3987/r-1986-05-1287
Abstract
Optically active piperazine 1 is synthesized in relatively high yield by the reduction of cyclo-L-Phe-L-Phe with sodium borohydride-titanium tetrachloride.Keywords
This publication has 1 reference indexed in Scilit:
- Organic chemistry of L-tyrosine. 1. General synthesis of chiral piperazines from amino acidsThe Journal of Organic Chemistry, 1985