Effect of Magnesium Deficiency on Synthesis of Heart and Liver Mitochondria Phospholipids

Abstract
1. the effect of magnesium deficiency on synthesis of heart and liver mitochondria phospholipids was studied in young rats. 2. A statistically signifisant decrease occurred in synthesis of total heart mitochondria phospholipids after 4 days of magnesium deficiency. However, there was no change in synthesis of phospholipids in the liver. 3. A decrease in phosphatidyl inositol, serine, ethanolamine, sphingomyelin and lecithin concentration in heart mitochondria occurred during development of magnesium deficiency. A decreased synthesis occurred in lecithin, sphingomyelin and phosphatidyl inositol fractions.