Abstract
Mice of various wts. were inoculated intraperit. with large nos. of type I pneumococci and the infections allowed to proceed until 5-10% of the animals had succumbed. The survivors were divided into groups at random and treated with penicillin and penicillin plus potent adrenal cortical extract. No improvement was obtained in the therapeutic results achieved with penicillin by the additional treatment with adrenal cortical extract.

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