In vivo Uptake and Retention of Fluoride in Human Surface Enamel after Application of a Fluoride-Containing Lacquer (Fluor Protector®)

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Abstract
The ability of a newly developed urethane lacquer containing silane fluoride (Fluor Protector®) to deposit fluoride in the enamel was tested in vivo using the enamel biopsy technique. The enamel fluoride concentration was measured before, 1 week after a single application or two applications of the lacquer performed with a 1-week interval, and 6 months after two applications. At the depths of 0.5 and 2.0 μm from the enamel surface, the mean fluoride levels increased by about 1,600 and 1,200 ppm (p < 0.001), respectively, after one application, and about 2,800 and 1,800 ppm (p < 0.002), respectively, after two applications. 6 months after two applications, 701 and 50% (p < 0.001) of the fluoride acquired at the two depths, respectively, seemed to be lost, indicating that a substantial part of the fluoride retained 1 week after treatment was not permanently bound in the enamel.

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