Catabolism of Antibody and of Serum Albumin and Globulin
- 30 September 1953
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 175 (1) , 147-152
- https://doi.org/10.1152/ajplegacy.1953.175.1.147
Abstract
The rate of disappearance of passively-transferred antibody, albumin and globulin has been followed in rabbits, using S35-L-methionine and I131-human serum albumin. The half-life of all materials studied by either method was about 6 days over the 2-week period investigated. Computation of the half-life for protein hydrolysis from theoretical kinetic data gave a value of 5-8 days.Keywords
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