Syntheses of sugars with a chirally deuterated hydroxymethyl group. Part II. The synthesis of D-(6R)- and (6S)-(6-2H1)-galactose.

Abstract
D-(6R)- and (6S)-(6-2H1)-Galactose were regio- and stereospecifically synthesized through photobromination of 1, 6-anhydrogalactose derivatives. The (6S)-compound was prepared in a similar manner to our previous synthesis of D-(6S)-(6-2H1)-glucose. The inversion to the (6R)-galacto derivatives was performed via (6S)-(6-2H1)-6-ρ-toluenesulfonyl-l, 2;3, 4-di-O-isopropyridene-α-D-galactose.

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