Radiation-Induced Salivary Gland Tumors: Report of a Case

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Abstract
• I discuss radiation-induced salivary gland tumors, with special emphasis on those tumors thought to be secondary to childhood head and neck irradiation for benign diseases. I report such a case and review the literature. Statistically, 77.6% of irradiation-induced tumors occur in the parotid gland and 22.4% in the submaxillary and minor salivary glands. A greater proportion of malignant tumors are noted in the submaxillary and minor salivary glands. At present, there is no demonstrable relationship between tumor occurrence and the amount of radiation received. Young children are more susceptible to irradiation-induced salivary tumors than older individuals. (Arch Otolaryngol 102:561-562, 1976)