RNA localization
- 15 September 2005
- journal article
- Published by The Company of Biologists in Journal of Cell Science
- Vol. 118 (18) , 4077-4081
- https://doi.org/10.1242/jcs.02543
Abstract
MRNA transcripts are coated by a variety of RBPs. Some of these are essential for mRNA localization and can be detected even when the mRNA is still nuclear. In many cases, specific sequence elements, `zipcodes', in the untranslated region (UTR) form a secondary structure that serves as a docking site for the RBPs and thus promotes the localization process.Keywords
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