Influence of path length on remote optical sensing of properties of biological tissue
- 15 June 1989
- journal article
- Published by Optica Publishing Group in Applied Optics
- Vol. 28 (12) , 2238-2244
- https://doi.org/10.1364/ao.28.002238
Abstract
A photon migration model is applied to the analysis of remote-sensing techniques that use light to probe the properties of biological tissues. Specific consideration is given to the effect of photon path length on the signals obtained from laser Doppler detection of blood flow in tissue microvasculature. We show how changes in blood volume or variation in spacing between delivery and detecting fibers might affect the measurements. We also examine how changes in path length can affect parameters determined by time resolved optical spectroscopy of blood oxygenation. Anisotropies in the angular distribution of scattered photons are taken into account.Keywords
This publication has 12 references indexed in Scilit:
- Statistics of Penetration Depth of Photons Re-emitted from Irradiated TissueJournal of Modern Optics, 1989
- Time-resolved spectroscopy of hemoglobin and myoglobin in resting and ischemic muscleAnalytical Biochemistry, 1988
- Photon migration in layered mediaApplied Optics, 1988
- Comparison of time-resolved and -unresolved measurements of deoxyhemoglobin in brain.Proceedings of the National Academy of Sciences, 1988
- Optical propagation in tissue with anisotropic scatteringIEEE Transactions on Biomedical Engineering, 1988
- Diffusing wave spectroscopyPhysical Review Letters, 1988
- Multiple light scattering from disordered media. The effect of brownian motion of scatterersZeitschrift für Physik B Condensed Matter, 1987
- Model for photon migration in turbid biological mediaJournal of the Optical Society of America A, 1987
- Response of nasal blood flow to neurohormones as measured by laser-Doppler velocimetryJournal of Applied Physiology, 1984
- Model for laser Doppler measurements of blood flow in tissueApplied Optics, 1981