PATHOLOGY OF MUCINOUS OVARIAN CYSTADENOMAS .1. ARGYROPHIL AND ARGENTAFFIN CELLS AND EPITHELIAL MUCOSUBSTANCES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 86  (6) , 465-470
Abstract
The presence of argyrophil and argentaffin cells and epithelial mucosubstances was studied in 187 mucinous ovarian cystadenomas of varying malignancy. Of the benign tumors 62% contained these cells. The corresponding figures for tumors of borderline malignancy and malignant tumors were 60% and 51% respectively. The epithelial cells of the mucinous cystadenomas characteristically contained periodic acid Schiff reactive and diastase resistant secretory material mixed with acid mucin which contained both sulphate and carboxyl groups. The amount of mucin diminished with increasing malignancy as did the ratio of neutral to acid mucins. Mucin histochemistry in tumors with and without argyrophil cells in a given group of malignancy was similar and the ages of the patients having those tumors did not differ significantly.

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