The Relationship Between Magnitude of Proteinuria Reduction and Risk of End-stage Renal Disease
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Open Access
- 25 April 2005
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 165 (8) , 947-953
- https://doi.org/10.1001/archinte.165.8.947
Abstract
A review of observational studies1-4 demonstrates that the magnitude of urinary protein excretion is associated with a linear increase in the risk of cardiovascular events and progression to end-stage renal disease (ESRD). During the past decade, there has been speculation that interventions that reduce proteinuria are more likely to slow the progression of renal disease in diabetic and nondiabetic patients.5-9Keywords
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