Initial Mushroom Tyrosinase‐Catalysed Oxidation Product of 4‐Hydroxyanisole is 4‐Methoxy‐Ortho‐Benzoquinone
- 1 May 1988
- journal article
- Published by Wiley in Pigment Cell Research
- Vol. 1 (6) , 379-381
- https://doi.org/10.1111/j.1600-0749.1988.tb00138.x
Abstract
Evidence is presented that the first and major product of the oxidation of 4-hydroxyanisole (4HA) by tyrosinase is 4-methoxy ortho benzoquinone (4-MOB). 4-MOB was synthesized by oxidation of 4HA by potassium nitrodisulphonate and comparisons made between the synthetic quinone and an extract of a reaction mixture in which 4HA had been completely oxidized by mushroom tyrosinase. The chemical species were found to be identical in UV/visible absorption spectrum, 1H-NMR spectrum, and by thin-layer chromatography.Keywords
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