Quantitation of left-to-right shunt from a single earpiece dye-dilution curve

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Abstract
A method for quantitatlon of left-to-right shunt in congenital heart disease by using an earpiece dye-dilution curve was presented. The principle consists of an estimation of concentration area of an abnormal hump on the downslope and its comparison with the area under the 1st circulated dye curve. The downslope of the 1st dye curve was determined by combining of Hetzel''s forward-triangle method and Lilienfield-Kovach''s method for calculation of dye-concentration area. To test the validity of this method, the calculated shunted values were compared to those obtained by means of the O2 step-up method in 40 patients. The values from these 2-methods were in a good agreement with each other. The effect of injection sites of dye on the calculated values of the shunt was proved to be insignificant. Major advantages of the present method were simplicity, promptness, and accuracy in quantitating left-to-right shunt regardless of its magnitude.

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