A New Epimeric Pair of Mono-THF Annonaceous Acetogenins fromGoniothalamus gardneri
- 1 April 1998
- journal article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 64 (03) , 242-245
- https://doi.org/10.1055/s-2006-957418
Abstract
From the roots of Goniothalamus gardneri Hook f. et. Thoms (Annonaceae), we have isolated a novel epimeric pair, gardnerinin ( 1) and 34- EPI-gardnerinin ( 1'), characterized by the presence of a gamma-hydroxymethyl-gamma-lactone moiety. These compounds represent an unusual type of mono-THF Annonaceous acetogenins, bearing one flanking hydroxy group on the hydrocarbon side, and another hydroxy group on the lactone side, that is only one carbon away from the THF ring.Keywords
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