The Effects of Chemical and Physical Agents on Filariform Larvae of Ancylostoma Braziliense
- 1 July 1959
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 8 (4) , 401-404
- https://doi.org/10.4269/ajtmh.1959.8.401
Abstract
Summary A study in vitro was performed, testing 183 compounds against the filariform larvae of Ancylostoma braziliense. As previous workers had found, the larvae are resistant to many commonly used parasiticides. Among the organic phosphates, Co-ral (O,O-diethyl O-(3-chloro-4-methyl-7-coumarinyl) phosphorothioate) and malathion had activity which might be of practical value in the treatment of human infections and for application to contaminated soil. Dilan among the chlorinated hydrocarbons, chlorpromazine among the phenothiazines and Vapam® among the nematocides showed similar activity. The importance of spontaneous cure of creeping eruption in the evaluation of drug therapy is discussed.Keywords
This publication has 3 references indexed in Scilit:
- Wandering Nematodes as a cause of Disability and DiseaseThe American Journal of Tropical Medicine and Hygiene, 1957
- Observations on the Reactions of the Larvae of Ancylostoma canium and Ancylostoma braziliense to Various Drugs and Chemical Compounds Based on In Vitro TestsJournal of Investigative Dermatology, 1953
- SYSTEMIC TREATMENT OF CREEPING ERUPTIONArchives of Dermatology, 1947