The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: The role of gut CYP3A and P-glycoprotein

This publication has 14 references indexed in Scilit:

• 6 ́,7 ́-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein
  Clinical Pharmacology & Therapeutics, 1999
• Role of P-Glycoprotein and Cytochrome P450 3A in Limiting Oral Absorption of Peptides and Peptidomimetics†
  Journal of Pharmaceutical Sciences, 1998
• THE PHARMACOLOGICAL ROLE OF P-GLYCOPROTEIN IN THE INTESTINAL EPITHELIUM
  Pharmacological Research, 1998
• Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man
  British Journal of Clinical Pharmacology, 1998
• Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*
  Clinical Pharmacology & Therapeutics, 1997
• Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation*
  Clinical Pharmacology & Therapeutics, 1996
• Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity
  Journal of Chromatography B: Biomedical Sciences and Applications, 1996
• Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P‐glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
  Molecular Carcinogenesis, 1995
• Disposition of intravenous and oral cyclosporine after administration with grapefruit juice*
  Clinical Pharmacology & Therapeutics, 1995
• Determination of dextromethorphan and dextrorphan in urine by high-performance liquid chromatography after solid-phase extraction
  Journal of Pharmaceutical and Biomedical Analysis, 1991