Abstract
Observational tests during the next decade may determine if the evolution of the Universe can be understood from fundamental physical principles, or if special initial conditions, coincidences, and new, untestable physical laws must be invoked. The inflationary model of the Universe is an important example of a predictive cosmological theory based on physical principles. In this article, we discuss the distinctive fingerprint that inflation leaves on the cosmic microwave background anisotropy. We then suggest a series of five milestone experimental tests of the microwave background which could determine the validity of the inflationary hypothesis within the next decade.

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