Epigenetics: A Challenge for Genetics, Evolution, and Development?
- 1 December 2002
- journal article
- review article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 981 (1) , 1-6
- https://doi.org/10.1111/j.1749-6632.2002.tb04909.x
Abstract
Abstract: In this paper, it is argued that differences in how one relates the genome to its surrounding contexts leads to diverse interpretations of the term epigenetics. Three different approaches are considered, ranging from gene‐centrism, over gene‐regulation, to dynamic systems approaches. Although epigenetics receives its widest interpretation in a systems approach, a paradigmatic shift has taken place in biology from the abandonment of a gene‐centric position on to the present. The epistemological and ontological consequences of this shift are made explicit.Keywords
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