Progressive Multifocal Leukoencephalopathy in a Child with Severe Combined Immunodeficiency

Publisher Website
Google Scholar
Abstract
To the Editor: Progressive multifocal leukoencephalopathy,1 a generally fatal demyelinating disease, tends to occur as a late opportunistic infection in immunodeficient adults. These patients have often suffered from leukemias, from granulomas or solid neoplasms of the reticuloendothelial system or from other cancers2 and have been treated with cytotoxic agents, irradiation or steroids or some combination of the above. A few patients have been on prolonged immunosuppressive therapy as a result of renal transplantation. Two young adults,3 , 4 18 and 22 years of age, had had immunologic deficiencies since childhood. The virus identified in brain tissue of patients with progressive multifocal leukoencephalopathy . . .

This publication has 3 references indexed in Scilit: