Interrelated Effects of L-Lysine and other Dietary Factors on the Gastrointestinal Absorption of Calcium 45 in the Rat and Chick

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Abstract
Singly administered L-lysine and vitamin D promoted Ca45 absorption in the vitamin D-deficient rat. The combined effect of L-lysine and vitamin D was about the sum of the effects of the individual components. L-Lysine and lactose singly increased Ca45 absorption in the normal rat, and their combined effect was also additive. In contrast to the rat, L-lysine, L-arginine, and skim milk powder did not increase Ca45 absorption in the rachitic chick. Treatment of the rachitic chick with vitamin D resulted in nearly complete absorption of Ca45 in this species. For this reason, the combined effect of other substances with vitamin D could not be evaluated. Proportionally more of the absorbed Ca45 was found in the femurs of the vitamin D-supplemented rat than in the vitamin D-deficient rat. Vitamin D had no apparent effect on the deposition of absorbed Ca45 in the tibias of the rachitic chick.