An altered form of pp60c-src is expressed primarily in the central nervous system.
Open Access
- 1 November 1987
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 7 (11) , 4115-4117
- https://doi.org/10.1128/mcb.7.11.4115
Abstract
The expression of two forms of pp60c-src, pp60 and pp60+, was measured in the central nervous system (CNS) and the peripheral nervous system. Both forms were expressed in the CNS, whereas only pp60 was primarily detected in the peripheral nervous system. Our findings suggest that pp60+ may play a role in events important to the CNS.Keywords
This publication has 9 references indexed in Scilit:
- Accumulation of c-src mRNA is developmentally regulated in embryonic neural retina.Molecular and Cellular Biology, 1986
- Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product.Proceedings of the National Academy of Sciences, 1985
- Neurones express high levels of a structurally modified, activated form of pp60c-srcNature, 1985
- PP60C-SRC IS EXPRESSED IN HUMAN-FETAL AND ADULT BRAIN1985
- pp60c-src in the developing cerebellum.Molecular and Cellular Biology, 1985
- pp60c-src is developmentally regulated in the neural retinaCell, 1984
- Neural tissues express high levels of the cellular src gene product pp60c-src.Molecular and Cellular Biology, 1983
- EXPRESSION OF PP60C-SRC PROTEIN-KINASE IN ADULT AND FETAL HUMAN-TISSUE - HIGH ACTIVITIES IN SOME SARCOMAS AND MAMMARY CARCINOMAS1983
- The Expression in Eukaryotes of a Tyrosine Kinase Which is Reactive with pp60v-src AntibodiesDifferentiation, 1982