Phase I study of cisplatin and irinotecan combined with concurrent hyperfractionated accelerated thoracic radiotherapy for locally advanced non-small cell lung carcinoma
- 1 December 2005
- journal article
- research article
- Published by Springer Nature in International Journal of Clinical Oncology
- Vol. 10 (6) , 418-424
- https://doi.org/10.1007/s10147-005-0525-6
Abstract
Irinotecan, when combined with cisplatin, is an effective treatment for advanced non-small cell lung cancer (NSCLC). This constitutes a rationale for conducting a phase I study of chemoradiotherapy including this combination for locally advanced NSCLC.Keywords
This publication has 42 references indexed in Scilit:
- Phase III Study of the Eastern Cooperative Oncology Group (ECOG 2597): Induction Chemotherapy Followed by Either Standard Thoracic Radiotherapy or Hyperfractionated Accelerated Radiotherapy for Patients With Unresectable Stage IIIA and B Non–Small-Cell Lung CancerJournal of Clinical Oncology, 2005
- Concurrent Hyperfractionated Radiotherapy and Low-Dose Daily Carboplatin and Paclitaxel in Patients With Stage III Non–Small-Cell Lung Cancer: Long-Term Results of a Phase II StudyJournal of Clinical Oncology, 2005
- Toxicity of high-dose radiotherapy combined with daily cisplatin in non-small cell lung cancer: results of the EORTC 08912 phase I/II studyEuropean Journal Of Cancer, 2000
- Twice-Daily Compared with Once-Daily Thoracic Radiotherapy in Limited Small-Cell Lung Cancer Treated Concurrently with Cisplatin and EtoposideNew England Journal of Medicine, 1999
- Improved Survival in Stage III Non-Small-Cell Lung Cancer: Seven-Year Follow-up of Cancer and Leukemia Group B (CALGB) 8433 TrialJNCI Journal of the National Cancer Institute, 1996
- Radiation Therapy Oncology Group (RTOG) 88-08 and Eastern Cooperative Oncology Group (ECOG) 4588: Preliminary Results of a Phase III Trial in Regionally Advanced, Unresectable Non-Small-Cell Lung CancerJNCI Journal of the National Cancer Institute, 1995
- Radiotherapy alone versus combined chemotherapy and radiotherapy in unresectable non-small cell lung carcinomaLung Cancer, 1994
- Effects of Concomitant Cisplatin and Radiotherapy on Inoperable Non-Small-Cell Lung CancerNew England Journal of Medicine, 1992
- Radiation and Platinum Drug InteractionInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1985
- Analysis of platinum in biological materials by flameless atomic absorption spectrophotometryBiochemical Medicine, 1977