Faculty Opinions recommendation of Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway.
- 15 October 2014
- dataset
- Published by H1 Connect
- Vol. 127 (10) , 2227-38
- https://doi.org/10.3410/f.721984330.793500761
Abstract
This study, together with {1-3}, suggested that Wnt5a and Wnt11 are involved in planar cell polarity establishment in vertebrates, as they are in Drosophila. However, their mechanism for planar cell polarity establishment remains unclear, although one mechanism involving Wnt5a-mediated Vangl2 phosphorylation during digit formation in mouse limbs also involves Ror2, a receptor tyrosine kinase that does not appear to have a planar...Keywords
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