Extrapolation of animal toxicity to humans: Interspecies comparisons in drug development
- 1 October 1990
- journal article
- research article
- Published by Elsevier in Regulatory Toxicology and Pharmacology
- Vol. 12 (2) , 107-116
- https://doi.org/10.1016/s0273-2300(05)80052-2
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Pharmacokinetics for regulatory risk analysis: The case of 1,1,1-trichloroethane (methyl chloroform)Regulatory Toxicology and Pharmacology, 1989
- Pharmacokinetics for regulatory risk analysis: The case of trichloroethyleneRegulatory Toxicology and Pharmacology, 1988
- New Approaches to the Use of Pharmacokinetics in Toxicology and Drug DevelopmentHuman Toxicology, 1988
- Review of interspecies risk comparisonsRegulatory Toxicology and Pharmacology, 1988
- Animal Extrapolation and the Challenge of Human HeterogeneityJournal of Pharmaceutical Sciences, 1986
- Relevance of experimental studies to human risk.Environmental Health Perspectives, 1983
- Sources of Uncertainty in Pharmacokinetic PredictionJournal of Animal Science, 1983
- Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokineticsJournal of Pharmacokinetics and Biopharmaceutics, 1982
- Part VI. Difficulties in extrapolating data on metabolism of drugs from animal to manClinical Pharmacology & Therapeutics, 1962
- Quantitative Relations in the Physiological Constitutions of MammalsScience, 1949