An Important Toxic Effect of Digitalis Overdosage on the Vision
- 29 April 1965
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 272 (17) , 904-905
- https://doi.org/10.1056/nejm196504292721709
Abstract
IN 1785 William Withering, in his famous book entitled "An Account of the Foxglove," writing concerning the effects of digitalis (page 184), said that "the foxglove when given in very large and quickly repeated doses, occasions sickness, vomiting, purging, giddiness, confused vision, objects appearing green or yellow...."In the early 1820's Purkinje, the great Czech physician, also described the toxic effect of digitalis on the vision, especially the rosettes of light seen by the patient, and Cushny, professor of pharmacology in the University of Edinburgh, writing his noted book on digitalis, which was published in 1925, had this to say . . .Keywords
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