A new synthetic method for the preparation of 2,8-disubstituted oxocane derivatives: synthesis of lauthisan and laurenan

Abstract
The cis-disubstituted oxocanes lauthisan (1) and laurenan (2) have been prepared from the lactone precursors (9b) and (9a) respectively by a sequence in which the key steps were methylenation and stereoselective hydroboration of the resulting enol ethers (11b) and (11a).

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