Passage of Leukemic Cells across the Placenta

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Abstract
THE combination of acute leukemia and pregnancy has been recorded infrequently in a number of papers reviewing this subject.1 2 3 4 5 No cases of coincidental congenital leukemia present at birth in a child of a mother with leukemia have been cited.6 The long-term follow-up study of offspring of leukemic parents has only lately received attention.7 Yet observations on the hereditary and transmissible nature of leukemia support the indication for investigation of this situation.8 Desai and Creger,9 using quinacrine as a DNA label, have recently studied maternofetal passage of white blood cells and platelets in normal pregnant patients. The present report concerns a . . .