Stereospecific Interaction of a Novel Spirosuccinimide Type Aldose Reductase Inhibitor, AS-3201, with Aldose Reductase
- 22 June 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 40 (28) , 8216-8226
- https://doi.org/10.1021/bi0102813
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Novel, Highly Potent Aldose Reductase Inhibitors: (R)-(−)-2-(4-Bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine- 4-spiro-3‘-pyrrolidine-1,2‘,3,5‘-tetrone (AS-3201) and Its CongenersJournal of Medicinal Chemistry, 1998
- Studies on Human Aldose Reductase.Published by Elsevier ,1995
- Human placental aldose reductase: role of Cys-298 in substrate and inhibitor bindingBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994
- Origins of Fluorine Chemical Shifts in ProteinsJournal of the American Chemical Society, 1994
- Contribution of Hydration to Protein Folding ThermodynamicsJournal of Molecular Biology, 1993
- An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic ComplicationsScience, 1992
- Purification and characterization of the recombinant human aldose reductase expressed in baculovirus systemBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1991
- Validation of the general purpose tripos 5.2 force fieldJournal of Computational Chemistry, 1989
- An all atom force field for simulations of proteins and nucleic acidsJournal of Computational Chemistry, 1986
- The kinetics of enzyme-catalyzed reactions with two or more substrates or productsBiochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1963