Glucagon: An Incomplete and Biased Review with Selected References
Open Access
- 1 August 1973
- journal article
- Published by Oxford University Press (OUP) in American Zoologist
- Vol. 13 (3) , 613-623
- https://doi.org/10.1093/icb/13.3.613
Abstract
This review summarizes the biochemistry, mode of action, physiologic functions, and clinical usefulness of glucagon, with emphasis on its role as a mobilizer of glycogen and fat, when adequate amount of exogenous nutrients are unavailable (starvation, heavy exercise, neonatal state) or cannot be properly utilized (diabetes mellitus). The “anti-insulin” properties of glucagon and the lessons of comparative physiology are reviewed.Keywords
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