Abstract
Reports of the benefit derived from the methods of treatment of bronchial asthma are extremely diverse and often depend on the enthusiastic preconceptions of the physician, the psychic susceptibilities of the patient and the spontaneous tendency of the disease to remissions, aggravations and improvement. In the earlier work on anaphylaxis and protein sensitization, the parallel symptoms suggested asthma to be a phenomenon of anaphylaxis.1According to this view, a person who has asthma is sensitized to a definite substance, and an attack occurs every time this substance enters the circulation. In the actual processes which take place in nature, the effective doses may be infinitely small; and it may well be possible that the minute quantities contained in the emanations from horses, cats or guinea-pigs are sufficient to act as a toxic dose and cause the nonfatal stenosis of the bronchi evidently present in an asthmatic attack in man. Perhaps

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