Abstract
The rate of change decreases with temp. from 15[degree] C to 0[degree]. In frozen muscle at[long dash]2[degree] the rate is almost as great as at 15[degree], but at[long dash]10[degree] the rate is extremely slow. Between 0[degree] and[long dash]10[degree] there is a temp. where max. rate of change must obtain. At 0[degree] in muscle containing originally 0.6-0.85 gm. % glycogen an "equilibrium" state is attained at concs. of 0.40-0.45 gm. % lactic acid and 0.20-0.22 gm. % glycogen, the accumulated lactic acid corresponding to only 50-70% of the glycogen loss. With lower original glycogen concs. of less than 0.3 gm. % there is a continuous loss of glycogen and equally rapid accumulation of lactic acid until only a trace of glycogen remains.

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