THE PROPERTIES OF SONIC FRAGMENTS OF DEOXYRIBOSE NUCLEIC ACID
- 1 May 1958
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 44 (5) , 432-438
- https://doi.org/10.1073/pnas.44.5.432
Abstract
By exposing DNA solutions to 9-kilocycle sonic waves for varying times in the absence of oxygen, the molecules were degraded through double-chain scission, producing fragments having the base-paired helical structure intact. In this manner, homologous samples of DNA were produced that covered a 25-fold range in molecular weight. With these fragments, the molecular-weight dependence of the sedimentation constant, the intrinsic viscosity, and the radius of gyration were determined.This publication has 1 reference indexed in Scilit:
- The ultraviolet absorption of some degraded desoxyribonucleic acidsBiochimica et Biophysica Acta, 1954