White Coat Phenomenon in Patients Receiving Antihypertensive Therapy

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Abstract
The occurrence of the white coat phenomenon in hypertensive patients receiving drug therapy was determined in a consecutive series of 71 patients undergoing ambulatory blood pressure (ABP) recordings because of suspected differences between office and ambulatory values. Overall mean (±SEM) office blood pressure (BP) was 166 ± 2/95 ± 1 υ awake ABP 139 ± 2/86 ± 1 mm Hg. The white coat phenomenon [(office BP – ABP)≥20/10 mm Hg] was present in 52 of 71 patients: office BP 170 ± 3/96 ± 2 υ ABP 135 ± 2/83 ± 1 mm Hg. A marked white coat effect [(office BP – ABP)≥40/20 mm Hg] was seen in 22 patients with office BP being 178 ± 4/98 ± 3 υ ABP 131 ± 3/79 ± 2 mm Hg. The frequent occurrence of white coat phenomenon in these patients suggests that office BP readings may not always represent usual ABP in patients receiving chronic antihypertensive therapy. Am J Hypertens 1991;4:844–849

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