IDENTIFICATION OF PHARMACOLOGICALLY ACTIVE SUBSTANCES IN THE INDIAN STINGING NETTLE, URTICA PARVIFLORA (ROXB.)

Publisher Website
Google Scholar
Abstract
The presence of histamine, 5-hydroxytryptamine (5-HT), and acetylcholine has been demonstrated in the Indian stinging nettle, Urtica parviflora (Roxb.). In addition, the presence of a histamine-liberating substance is strongly indicated. The whole leaves of the plant were extracted in acetone. The acetone-extracted material was used to detect 5-HT and acetylcholine. The acid-treated extract was used for the detection of histamine, and the histaminase-treated extract was used for the detection of the histamine liberator. Appropriate biological and chromatographic tests were performed for the pharmacologically active constituents.