Multiple mucosal neuroma (MMN) or multiple endocrine neoplasia (MEN) type 3 syndrome
- 1 September 1977
- journal article
- case report
- Published by Springer Nature in Documenta Ophthalmologica
- Vol. 44 (1) , 151-159
- https://doi.org/10.1007/bf00171466
Abstract
Case report of a young man showing neuromas of the palpebral and bulbar conjunctiva and markedly thickened nerve fibers in both cornea. Multiple neuromas were seen on the lips and in the oral cavity. A medullary carcinoma of the thyroid was found. These symptoms pointed to the diagnosis of a MMN or MEN type 3 syndrome. There were no signs of a phaeochromocytoma, however, which also belongs to this syndrome. The ophthalmologist, who may be the first to see such a patient as a child, should be aware of the malignancies which develop around puberty and of the strong and dominant heredity of this disease.Keywords
This publication has 7 references indexed in Scilit:
- Mucosal neuroma, pheochromocytoma and medullary thyroid carcinoma: multiple endocrine neoplasia type 3.1975
- The APUD cell concept and its implications in pathology.1974
- Hypertrophy of peripheral nerves in the syndrome of multiple mucosal neuromas, endocrine tumours and Marfanoid habitus. Autonomic disturbances and sural nerve findings.1974
- Multiple mucosal neuromas, pheochromocytoma, medullary carcinoma of the thyroid and marfanoid body build with muscle wastingEuropean Journal of Pediatrics, 1972
- Clinical DemonstrationsOphthalmologica, 1970
- Multiple mucosal neuromata with endocrine tumours: A syndrome allied to von Recklinghausen's diseaseThe Journal of Pathology and Bacteriology, 1966
- Medullated corneal nerves and plexiform neuroma associated with pheochromocytoma.1954