Contribution à L'Étude D'Acides de la Série de la Pyridazine IV. ‐ Nouvel alcaloïde de synthèse, L'«aza‐2 nicotine»
- 1 January 1966
- journal article
- research article
- Published by Wiley in Bulletin des Sociétés Chimiques Belges
- Vol. 75 (1-2) , 5-16
- https://doi.org/10.1002/bscb.19660750102
Abstract
An exhaustive study of the different methods of synthesis of pyridazine 3‐carboxylic acid has been undertaken and two new preparations of this acid have been realized, one by carbonatation of 6‐chloro 3‐pyridazinyllithium, the other by permanganic oxidation of 6‐chloro 3‐pyrrolo pyridazine.The α‐(3‐pyridazinyl)‐N‐Methyl pyrrole or «2‐aza‐nicotine» is obtained from N‐methyl‐2‐pyrrolyllithium and 3,6‐dichloropyridazine.Keywords
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