Computer-assisted modeling of multiple dextromethorphan and sigma binding sites in guinea pig brain
- 25 April 1991
- journal article
- Published by Elsevier in European Journal of Pharmacology: Molecular Pharmacology
- Vol. 206 (4) , 261-269
- https://doi.org/10.1016/0922-4106(91)90108-t
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Sigma ligands bind in the guinea pig and rat brain to a high-affinity dextromethorphan site, which is allosterically modulated by ropizine and phenytoinEuropean Journal of Pharmacology, 1990
- Repizine concurrently enhances and inhibits [3H] dextromethorphan binding to different structures of the guinea pig brain: Autoradiographic evidence for multiple binding sitesLife Sciences, 1990
- Sigma receptors regulate contractions of the guinea pig ileum longitudinal muscle/myenteric plexus preparation elicited by both electrical stimulation and exogenous serotoninJournal of Neuroscience, 1989
- Evidence for a multi-site model of the rat brain σ receptorEuropean Journal of Pharmacology, 1989
- The effects of prototypic σ ligands on the binding of [3H]dextromethorphan to guinea pig brainNeuroscience Letters, 1989
- Inhibition of rubral neurons by a specific ligand for σ receptorsEuropean Journal of Pharmacology, 1988
- Autoradiographic visualization of haloperidol-sensitive sigma receptors in guinea-pig brainNeuroscience, 1988
- A very high affinity opioid binding site in rat brain: Demonstration by computer modelingBiochemical and Biophysical Research Communications, 1984
- New Methods for Characterization of Complex Receptor Systems Involving 3 or More Binding Sites: Application to Brain Opiate ReceptorsJournal of Receptor Research, 1984
- LIGAND: A versatile computerized approach for characterization of ligand-binding systemsAnalytical Biochemistry, 1980