URINARY-TRACT INFECTIONS DUE TO STAPHYLOCOCCUS-SAPROPHYTICUS BIOTYPE-3

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  • 1 January 1981
    • journal article
    • research article
    • Vol. 124  (4) , 415-418
Abstract
Urinary isolates of S. saprophyticus were presumptively differentiated from other coagulase-negative Micrococcaceae by their resistance to novobiocin as demonstrated by a simple disc susceptibility test that misidentified the infecting organism in only 3.4% of specimens. These novobiocin-resistant, coagulase-negative organisms caused similar proportions of the urinary tract infections in young women in York, England, UK, and Vancouver, British Columbia, Canada, 6.6% and 6.9%, respectively. In York, these organisms were associated with significantly greater pyuria than novobiocin-sensitive organisms or bile-tolerant streptococci but not S. aureus or Enterobacteriaceae. In both communities novobiocin-sensitive, coagulase-negative Micrococcaceae were appreciably more resistant to penicillin than novobiocin-resistant organisms. Thus, differentiating S. saprophyticus from novobiocin-sensitive coagulase-negative organisms provides information that is clinically useful, particularly for primary care practitioners working in the community or in outpatient clinics.