Abstract
For study of problems of the physiology of the liver and organs whose venous blood drains into the portal system, this method is accomplished by 2-stage operation in the dog, cat, goat, rabbit or rat: the portal vein is isolated and 2 strong linen threads are introduced around it above the entrance of the pancreatic-duodenal branch; one is then tied sufficiently to produce a constriction of the vein to about 1/2 of its diam. A slight congestion of the intestines may occur which rapidly disappears. The ends of the second thread are then fastened to the abdominal wall so they may be readily found at the second operation. The 2nd operation may be done 2-3 weeks later.

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