PRACTICAL CONTROL OF FLUID AND ELECTROLYTE BALANCE IN CARBON TETRACHLORIDE NEPHROSIS

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Abstract
IT IS THE purpose of this paper to relate our experiences with seven cases of poisoning due to carbon tetrachloride seen at the United States Public Health Service Hospital, Boston, during a period of 18 months. Although many excellent textbooks of medicine1 make no mention of this condition, it has been commoner at this hospital than such thoroughly discussed diseases as typhoid and diphtheria. Many of the early clinical descriptions of carbon tetrachloride poisoning have emphasized the hepatic damage,2 but in recent years the capacity of this substance to produce the picture of lower nephron nephrosis has been recognized more frequently. It has been our experience that carbon tetrachloride poisoning, as is the case with so many other diseases, often is not diagnosed because it is not considered in the differential diagnosis and, therefore, a history of exposure is not sought. The necessity of accurate diagnosis with simple

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