Inhibition of Streptococcal Hemolysin by Sulfonamide Compounds
- 1 March 1938
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 38 (2) , 275-279
- https://doi.org/10.3181/00379727-38-9818
Abstract
Conclusions Sulfanilamide causes a slight, almost negligible, inhibition of the hemolytic activity of streptococcal and staphylococcal hemotoxin. More marked inhibition of streptococcal hemolysin is produced by prontosil II, normal rabbit serum, rabbit Serum heated to 61°C., eosin, phenol, mercuric chloride, and sodium carbonate. The administration of sulfanilamide in vivo or its addition to serum in vitro does not enhance the inhibitory effect of rabbit serum upon streptococcal hemolysin. Prontosil I was found to have no inhibitory effect upon streptococcal hemolysin.Keywords
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