CLINICAL COMPARISON OF TECHNETIUM-99M DIPHOSPHONATE AND PYROPHOSPHATE IN BONE SCINTIGRAPHY - CONCISE COMMUNICATION

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 19  (2) , 161-163
Abstract
Patients (30) had bone scintigraphy with both 99mTc pyrophosphate (Tc-PPi) and 99mTc diphosphonate (Tc-HEDP). The images were given a composite rating for quality on the basis of 3 sets of criteria and were also compared for the number of lesions detected by each agent. The 2 agents provided no difference in scan quality. Nevertheless, in 10 of the 30 patients, at least 2 of the 3 readers detected with Tc-HEDP lesions that were not seen with Tc-PPi and in 2 such cases all 3 readers considered the Tc-PPi scan normal. In another of these 10, 2 of the 3 readers felt the Tc-PPi image was normal, whereas all 3 detected the lesion with Tc-HEDP. The reverse never occurred (P < 0.01).